How the Sugar Industry Manipulated Science to Hide the Truth About Heart Disease

For decades, dietary fat was public enemy number one when it came to heart disease. Government guidelines, doctors, and nutrition experts warned against butter, red meat, and eggs while giving sugar a free pass. But what if this narrative wasn’t based on unbiased science?
A groundbreaking 2016 study published in JAMA Internal Medicine uncovered shocking evidence that the sugar industry secretly funded research in the 1960s to downplay sugar’s role in heart disease and shift blame to fat. Internal documents from the Sugar Research Foundation (SRF) reveal a deliberate campaign to manipulate science, influence policymakers, and protect profits—at the expense of public health.
This essay explores how the sugar industry shaped the heart disease debate, the long-term consequences of their actions, and why this history matters for health-conscious individuals today.
The Sugar Industry’s Hidden Agenda
In the 1950s, heart disease was skyrocketing in the U.S., and scientists were racing to understand why. Two competing theories emerged:
- The Fat Hypothesis – Led by physiologist Ancel Keys, this camp argued that saturated fat and cholesterol were the primary drivers of heart disease.
- The Sugar Hypothesis – British researcher John Yudkin and others warned that sugar—particularly sucrose—was a major culprit, raising cholesterol and triglycerides.
The sugar industry saw Yudkin’s work as a threat. Internal memos show that SRF executives were alarmed by studies suggesting sugar was worse than starch for heart health. Instead of addressing these concerns, they devised a plan to shape the scientific narrative in their favor.
Project 226: Buying Science to Protect Profits
In 1965, the SRF quietly funded a Harvard research team to conduct a literature review on sugar, fat, and heart disease. The study, published in the New England Journal of Medicine (NEJM) in 1967, concluded that the only dietary change needed to prevent heart disease was reducing saturated fat—while dismissing sugar’s risks.
Key revelations from the 2016 investigation:
- The SRF handpicked studies to include in the review, ensuring sugar-friendly conclusions.
- Researchers were paid by the sugar industry, but this conflict of interest was never disclosed.
- Unfavorable studies were downplayed, including those linking sugar to elevated triglycerides and cholesterol.
This biased review became a cornerstone of nutritional advice for decades, helping to exonerate sugar while demonizing fat.
How the Sugar Industry Controlled the Narrative

1. Attacking Critics and Funding Friendly Science
The SRF didn’t just fund its own research—it actively worked to discredit scientists like Yudkin. Internal documents show they planned to:
- Organize a symposium to publicly “unveil the fallacies” of sugar critics.
- Commission polls to identify public misconceptions they needed to “combat.”
- Replicate studies in ways that would “refute our detractors.”
2. Shifting the Focus to Fat
In a 1954 speech, SRF president Henry Hass admitted their strategy:
“If the public could be persuaded to eat a lower-fat diet, they would need to replace those calories with something—and sugar was the perfect candidate.”
By pushing the low-fat message, the sugar industry ensured that processed foods—often loaded with added sugars—would dominate the market.
3. Influencing Policy and Public Perception
The SRF’s tactics didn’t stop with research. They also:
- Lobbied government agencies to focus on fat, not sugar, in dietary guidelines.
- Funded dental research to downplay sugar’s role in cavities.
- Continued denying sugar’s harms for decades, despite mounting evidence.
The Consequences: How Misinformation Shaped Our Diets

The sugar industry’s manipulation had lasting effects:
1. The Low-Fat Boom (and Sugar Surge)
- In the 1980s and 1990s, “low-fat” products flooded supermarkets—but many were packed with added sugars to improve taste.
- Sugar consumption soared, contributing to obesity and diabetes epidemics.
2. Delayed Recognition of Sugar’s Dangers
- It took until the 21st century for major health organizations to acknowledge that added sugars (not just fat) drive heart disease.
- Even today, many people still believe fat is the primary enemy, while underestimating sugar’s risks.
3. Eroding Trust in Nutrition Science
- The sugar scandal is part of a larger pattern: industries (like tobacco and soda) funding research to protect profits.
- It highlights why transparency in science is crucial—consumers deserve to know who’s behind the studies they read.
Lessons for Health-Conscious Consumers
1. Follow the Money
- Be skeptical of industry-funded studies. Check disclosures in research papers.
- Look for consensus among independent scientists, not just single studies.
2. Sugar’s Real Impact on Heart Health
Modern research confirms what Yudkin warned:
- Excess sugar raises triglycerides, a key heart disease risk factor.
- Fructose (in sucrose and high-fructose corn syrup) promotes inflammation and insulin resistance.
- Sugar-heavy diets contribute to obesity, diabetes, and fatty liver disease—all linked to heart problems.
3. A Balanced Approach to Heart Health
Instead of fearing all fats or all sugars, focus on:
- Minimizing added sugars (sodas, pastries, processed foods).
- Choosing healthy fats (avocados, nuts, olive oil) over trans fats and excessive saturated fats.
- Eating whole, unprocessed foods—nature’s best defense against heart disease.
Summary
The sugar industry’s manipulation of heart disease research is a cautionary tale about corporate influence on science. For decades, their hidden tactics shifted blame away from sugar, contributing to misguided dietary advice and worsening public health.
Today, we know better—but the fight isn’t over. Big Food still funds biased studies, and sugar remains a major driver of chronic disease. As health-conscious individuals, we must stay informed, question industry narratives, and demand transparency in nutrition research.